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Antigenic Specificity | Human Proliferation-associated protein 2G4 |
Clone | [PAT5E7AT] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 heavy chain and k light chain. |
Format | Protein A purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PA2G4 belongs to the peptidase M24C family and functions as an RNA-binding protein involved in cellular proliferation and differentiation processes. PA2G4 is a component of pre-ribosomal ribonucleoprotein complexes, participating in ribosome assembly and regulating the later steps of rRNA processing. Also, PA2G4 interacts with ErbB-3 and may function as a modulator of the ErbB-3 mediated signal transduction pathway by regulating the effects of Neuregulin-1. Furthermore, PA2G4 is a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. PA2G4 is implicated in growth inhibition and the induction of differentiation of human cancer cells. In addi |
Immunogen | Immunogen: Anti-human PA2G4 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PA2G4 protein 1-394 amino acids purified from E Coli. |
Other Names | [PA2G4; Proliferation-associated protein 2G4; Cell cycle protein p38-2G4 homolog; hG4-1; ErbB3-binding protein 1; PA2G4; EBP1; p38-2G4; Proliferation-associated protein 2G4, Mouse Human], [PA2G4; PA2G4; EBP1; HG4-1; p38-2G4; EBP1; hG4-1] |
Gene, Accession # | [PA2G4], Gene ID: 5036, NCBI: NP_006182.2, UniProt: Q9UQ80 |
Catalog # | MBS146690 |
Price | $140, $205, $505 |
Order / More Info | Human Proliferation-associated protein 2G4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |