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Antigenic Specificity | LRP5 (C-term), 1163-1190 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This LRP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1163-1190 amino acids from the C-terminal region of human LRP5. This gene encodes a transmembrane low-density lipoproteinreceptor that binds and internalizes ligands in the process ofreceptor-mediated endocytosis. This protein also acts as aco-receptor with Frizzled protein family members for transducingsignals by Wnt proteins and was originally cloned on the basis ofits association with type 1 diabetes mellitus in humans. Thisprotein plays a key role in skeletal homeostasis and many bonedensity related diseases are caused by mutations in this gene.Mutations in this gene also cause familial exudativevitr |
Immunogen | n/a |
Other Names | [Low-density lipoprotein receptor-related protein 5; LRP-5; LRP5; LR3; LRP7] |
Gene, Accession # | [LRP5], Gene ID: 4041, NCBI: NP_002326.2, UniProt: O75197 |
Catalog # | MBS9210380 |
Price | $165, $370 |
Order / More Info | LRP5 (C-term), 1163-1190 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Lee, D.Y., et al. Menopause 17(5):1064-1070(2010) Liu, J.M., et al. J. Clin. Endocrinol. Metab. 95 (9), E112-E120 (2010) : Paternoster, L., et al. J. Clin. Endocrinol. Metab. 95(8):3940-3948(2010) Stathopoulou, M.G., et al. J Am Diet Assoc 110(7):1078-1083(2010) |