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Antigenic Specificity | Phospho-Mouse TSC1 (T310) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.3 |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T310 of mouse TSC1. In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity). |
Immunogen | n/a |
Other Names | [Hamartin; Tuberous sclerosis 1 protein homolog; Tsc1; Kiaa0243] |
Gene, Accession # | [Tsc1], Gene ID: 64930, NCBI: NP_075025.2, UniProt: Q9EP53 |
Catalog # | MBS9212511 |
Price | $165, $370 |
Order / More Info | Phospho-Mouse TSC1 (T310) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kladney, R.D., et al. Cancer Res. 70(21):8937-8947(2010) Sathaliyawala, T., et al. Immunity 33(4):597-606(2010) Scott, C.L., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 299 (4), L455-L471 (2010) : Bartolome, A., et al. Endocrinology 151(7):3084-3094(2010) Squarize, C.H., et al. PLoS ONE 5 (5), E10643 (2010) : |