Phospho-Mouse TSC1 (T310) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-Mouse TSC1 (T310)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.3
ApplicationsDot Blot (DB), ELISA (EIA)
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DescriptionThis mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T310 of mouse TSC1. In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Immunogenn/a
Other Names[Hamartin; Tuberous sclerosis 1 protein homolog; Tsc1; Kiaa0243]
Gene, Accession #[Tsc1], Gene ID: 64930, NCBI: NP_075025.2, UniProt: Q9EP53
Catalog #MBS9212511
Price$165, $370
Order / More InfoPhospho-Mouse TSC1 (T310) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKladney, R.D., et al. Cancer Res. 70(21):8937-8947(2010) Sathaliyawala, T., et al. Immunity 33(4):597-606(2010) Scott, C.L., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 299 (4), L455-L471 (2010) : Bartolome, A., et al. Endocrinology 151(7):3084-3094(2010) Squarize, C.H., et al. PLoS ONE 5 (5), E10643 (2010) :
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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