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Antigenic Specificity | NOD5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-kB and JNK pathways by inducing reactive oxygen species production. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 14 amino acid peptide near the amino terminus of human NOD5. |
Other Names | [Nucleotide-binding oligomerization domain containing 5, NOD9, NOD26, DLNB26, CLR11.3, NLRX1] |
Gene, Accession # | [NOD5], Gene ID: 79671, NCBI: NP_078894 |
Catalog # | MBS9413331 |
Price | $320 |
Order / More Info | NOD5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |