Phospho-ErbB2 (Y1112) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Phospho-ErbB2 (Y1112) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Dot Blot (DB), ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This ErbB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1112 of human ErbB2. ErbB2 is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of this gene has been reported in numerous can |
| Immunogen | n/a |
| Other Names | [Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD340; ERBB2; HER2; MLN19; NEU; NGL] |
| Gene, Accession # | [ERBB2], Gene ID: 2064, NCBI: NP_001005862.1, UniProt: P04626 |
| Catalog # | MBS9204680 |
| Price | $165, $370 |
| Order / More Info | Phospho-ErbB2 (Y1112) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Stephens, P., et al., Nature 431(7008):525-526 (2004). Wang, S.C., et al., Cancer Cell 6(3):251-261 (2004). Menendez, J.A., et al., Proc. Natl. Acad. Sci. U.S.A. 101(29):10715-10720 (2004). M, et al., Anticancer Res. 24(4):2219-2224 (2004). Contreras, D.N., et al., Clin. Appl. Thromb. Hemost. 10(3):271-276 (2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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