TFE3 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | TFE3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total TFE3 protein. Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.Clark J., Oncogene 15:2233-2239(1997).Sidhar S.K., Hum. Mol. Genet. 5:1333-1338(1996).Beckmann H., Genes Dev. 4:167-179(1990). |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human TFE3. |
| Other Names | [Transcription factor E3; TFE3] |
| Gene, Accession # | [TFE3], Gene ID: 7030, NCBI: NP_001269071.1, UniProt: P19532 |
| Catalog # | MBS9406349 |
| Price | $200, $255 |
| Order / More Info | TFE3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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