Edit |   |
---|---|
Antigenic Specificity | TSYL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TSYL2 antibody detects endogenous levels of total TSYL2. Function: Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.Subunit Structure: Interacts with histones. Interacts with CASK. Part of a complex containing CASK, TBR1 and TSPYL2 (By similarity).Post-translational Modifications: Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation.Similarity: Belongs to the nucleosome assembly protein (NAP) family. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Cytoplasm. Enriched in transcriptionally active regions of chromatin in neurons. Tissue Specificity: Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas. |
Other Names | [CASK interacting nucleosome assembly protein; CDA1; Cell division autoantigen 1; CINAP; CTCL; CTCL tumor antigen se20 4; CTCL-associated antigen se20-4; Cutaneous T cell lymphoma associated antigen se20 4; Cutaneous T cell lymphoma associated tumor antigen se20 4; Cutaneous T-cell lymphoma-associated antigen se20-4; Differentially Expressed Nucleolar TGF beta1 Target; Differentially Expressed Nucleolar TGF beta1 Target protein; Differentially-expressed nucleolar TGF-beta1 target protein; HRIHFB2216; NP79; Nuclear protein of 79 kDa; RP1 290F12.2; SE20 4; SE204; Testis specific protein Y encoded like 2; testis-specific protein Y encoded-like 2; Testis-specific Y-encoded-like protein 2; TSPX; TSPY like 2; TSPY like protein 2; TSPY-like protein 2; TSPYL2; TSYL2_HUMAN] |
Gene, Accession # | [TSYL2], Gene ID: 64061, NCBI: NP_071400.1, UniProt: Q9H2G4 |
Catalog # | MBS9603980 |
Price | $240, $280 |
Order / More Info | TSYL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |