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Antigenic Specificity | GABAA Receptor, alpha1-Subunit |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Dot blots (DB). Suitability for Immunohistochemistry (IHC) not yet determined. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Specific for the ~51k alpha1-subunit of the GABAA-R in Western blots of rat brain membrane fractions. Also recognizes the Alpha1-subunit of the GABAA-R in bovine, human and mouse brain extracts. Affinity purified rabbit polyclonal antibody |
Immunogen | Antigen: Fusion protein from the cytoplasmic loop of the alpha1-subunit of rat GABAA receptor. Immunogen Information: Fusion protein from the cytoplasmic loop of the alpha 1 subunit. Immunogen Species: Rat |
Other Names | [gamma-aminobutyric acid receptor subunit alpha-1; Gamma-aminobutyric acid receptor subunit alpha-1; gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; gamma-aminobutyric acid A receptor, alpha 1; gamma-aminobutyric acid A receptor, alpha 1; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1; gamma-aminobutyric acid (GABA) A receptor, alpha 1; GABA(A) receptor subunit alpha-1], [Gabra1; Gabra1; Gabra-1] |
Gene, Accession # | [GABRA1], Gene ID: 29705, NCBI: NP_899155.1, UniProt: P62813 |
Catalog # | MBS502042 |
Price | $360 |
Order / More Info | GABAA Receptor, alpha1-Subunit Antibody from MYBIOSOURCE INC. |
Product Specific References | • McKernan RM, et al. (2000) Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor alpha1-subtype. Nature Neurosci 3:587-592.• Mehta AK, Ticku MK (1998) Prevalence of the GABAA receptor assemblies containing alpha1-subunit in the rat cerebellum and cerebral cortex as determined by immunoprecipitation: Lack of modulation by chronic ethanol administration. Mol Brain Res 67:194-199.• Ogris W, Poltl A, Hauer B, Ernst M, Oberto A, Wulff P, Hoger H, Wisden W, Sieghart W (2004) Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABAA receptor gamma2-subunit. Biochem Pharmacol 68:1621-1629.• Mridula Rewal, Rachel Jurd, T. Michael Gill, Dao-Yao He, Dorit Ron, and Patricia H. Janak (2009) 4-Containing GABAA Receptors in the Nucleus Accumbens Mediate Moderate Intake of Alcohol J. Neurosci., 29: 543 - 549• Olsen RW, Tobin AJ (1990) Molecular biology of GABAA receptors. FASEB 4:1469-1480. |