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Antigenic Specificity | AIF-M1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AIF-M1 Polyclonal Antibody detects endogenous levels of AIF-M1 protein. AIFM1 encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product (apoptosis inducing factor, mitochondria associated 1) induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive C |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human AIF-M1 at AA range: 30-110 |
Other Names | [Rabbit AIF-M1; AIFM1; AIF; PDCD8; Apoptosis-inducing factor 1; mitochondrial; Programmed cell death protein 8] |
Gene, Accession # | [AIF-M1], NCBI: NP_001124318.1, UniProt: O95831 |
Catalog # | MBS9701352 |
Price | $130, $220, $325 |
Order / More Info | AIF-M1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |