GDNF Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGDNF
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThe antibody detects endogenous levels of GDNF protein. GDNF encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during tr
ImmunogenImmunogen: Synthesized peptide derived from part region of human GDNF protein at amino acid sequence of 100-180
Other Names[Rabbit GDNF; Glial cell line-derived neurotrophic factor; hGDNF; Astrocyte-derived trophic factor; ATF]
Gene, Accession #[GDNF], Gene ID: 2668, NCBI: NP_001265027.1, UniProt: P39905
Catalog #MBS9709202
Price$130, $220, $325
Order / More InfoGDNF Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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