Human GAPDH Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman GAPDH
Clone[4G5]
Host SpeciesMouse
Reactive Speciesbovine, cat, dog, fish, goat, mouse, porcine, rabbit, rat
IsotypeIgG1
Formatunconjugated
Size0.2 mg
ConcentrationIgG concentration 1.0mg/ml
ApplicationsImmunohistology Frozen, ELISA (EIA), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionMouse anti Human GAPDH antibody, clone 4G5 recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyse the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin.
ImmunogenImmunogen: Human cardiac muscle GADPH Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human
Other Names[glyceraldehyde-3-phosphate dehydrogenase isoform 2; Glyceraldehyde-3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase; aging-associated gene 9 protein; epididymis secretory sperm binding protein Li 162eP; peptidyl-cysteine S-nitrosylase GAPDH; glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase GAPDH (EC:2.6.99.-)], [GAPDH; GAPDH; G3PD; GAPD; HEL-S-162eP; GAPD; GAPDH]
Gene, Accession #[GAPDH], Gene ID: 2597, NCBI: NP_001243728.1
Catalog #MBS219475
Price$430
Order / More InfoHuman GAPDH Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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