Cyclin D1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Cyclin D1 antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | Cyclin D1 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for G1/S-specific cyclin-D1(CCND1) detection. Tested with WB in Human. Background: Cyclin D1, also known as CCND1, is a human gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein and promotes progression through the G1-S phase of the cell cycle. Amplification or overexpression of cyclin D1 plays pivotal roles in the development of a subset of human cancers including parathyroid adenoma, breast cancer, colon cancer, lymphoma, melanoma, and pros |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Cyclin D1 (158-184aa HDFIEHFLSKMPEAEENKQIIRKHAQT), different from the related mouse sequence by two amino acids, and from the related rat sequence by one amino acid. Ig Type: Rabbit IgG |
| Other Names | [G1/S-specific cyclin-D1; AI327039; B cell ccl/lymphoma 1; B cell CLL/lymphoma 1; B cell leukemia 1; B cell leukemia 1; B cell lymphoma 1 protein; B-cell lymphoma 1 protein; BCL 1; BCL-1; BCL-1 oncogene; BCL1; BCL1 oncogene; CCND 1; CCND1; CCND1 protein; CCND1/FSTL3 fusion gene, included; CCND1/IGHG1 fusion gene; CCND1/IGHG1 fusion gene, included; CCND1/IGLC1 fusion gene, included; CCND1/PTH fusion gene, included; CCND1_HUMAN; cD1; Cyl 1; D11S287E; G1/S specific cyclin D1; G1/S-specific cyclin-D1; Parathyroid adenomatosis 1; PRAD1; PRAD1 oncogene; U21B31; cyclin D1], [CCND1; CCND1; BCL1; PRAD1; U21B31; D11S287E; BCL1; PRAD1; BCL-1] |
| Gene, Accession # | Gene ID: 595, NCBI: NP_444284.1, UniProt: P24385 |
| Catalog # | MBS177801 |
| Price | $280 |
| Order / More Info | Cyclin D1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Fu, M.; Wang, C.; Li, Z.; Sakamaki, T.; Pestell, R. G. : Minireview: Cyclin D1: normal and abnormal functions. Endocrinology 145: 5439-5447, 2004. 2. Wang, C.; Pattabiraman, N.; Zhou, J. N.; Fu, M.; Sakamaki, T.; Albanese, C.; Li, Z.; Wu, K.; Hulit, J.; Neumeister, P.; Novikoff, P. M.; Brownlee, M.; Scherer, P. E.; Jones, J. G.; Whitney, K. D.; Donehower, L. A.; Harris, E. L.; Rohan, T.; Johns, D. C.; Pestell, R. G. : Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation. Molec. Cell. Biol. 23: 6159-6173, 2003. 3. Brisken, C.; Ayyannan, A.; Nguyen, C.; Heineman, A.; Reinhardt, F.; Tan, J.; Dey, S. K.; Dotto, G. P.; Weinberg, R. A. : IGF-2 is a mediator of prolactin-induced morphogenesis in the breast. Dev. Cell 3: 877-887, 2002. Note: Erratum: Dev. Cell 4: 283 only, 2003. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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