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Antigenic Specificity | ZC3HAV1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 14 amino acid peptide near the carboxy terminus of human ZC3HAV1. |
Other Names | [zinc finger CCCH-type antiviral protein 1, PARP13, ZAP, ZC3H2, ZC3HDC] |
Gene, Accession # | [ZC3HAV1], Gene ID: 56829, NCBI: NP_078901 |
Catalog # | MBS9405960 |
Price | $320 |
Order / More Info | ZC3HAV1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |