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Antigenic Specificity | PTPIA2 beta (N-term), 94-125 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PTPIA2 beta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-125 amino acids from the N-terminal region of human PTPIA2 beta. PTPIA2beta is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-depende |
Immunogen | n/a |
Other Names | [Receptor-type tyrosine-protein phosphatase N2; R-PTP-N2; Islet cell autoantigen-related protein; IAR; ICAAR; Phogrin; PTPRN2; KIAA0387] |
Gene, Accession # | [PTPRN2], Gene ID: 5799, NCBI: NP_002838.2, UniProt: Q92932 |
Catalog # | MBS9202110 |
Price | $165, $370 |
Order / More Info | PTPIA2 beta (N-term), 94-125 Antibody from MYBIOSOURCE INC. |
Product Specific References | Schmidli, R.S., et al., Autoimmunity 28(1):15-23 (1998). Li, Q., et al., Proc. Assoc. Am. Physicians 109(4):429-439 (1997). Cui, L., et al., J. Biol. Chem. 271(40):24817-24823 (1996). Kawasaki, E., et al., Biochem. Biophys. Res. Commun. 227(2):440-447 (1996). Smith, P.D., et al., Biochem. Biophys. Res. Commun. 229(2):402-411 (1996). |