INSR (Insulin Receptor) (N-term), 21-52 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityINSR (Insulin Receptor) (N-term), 21-52
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse, rat)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 1.48
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
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DescriptionThis INSR(Insulin Receptor) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-52 amino acids from the N-terminal region of human INSR(Insulin Receptor). INSR is a receptor that binds insulin and has a tyrosine-protein kinase activity. Autophosphorylation activates the kinase activity. This Type I mebrane protein is composed of a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. After being transported from the endoplasmic reticulum to the Golgi apparatus, the single glycosylated precursor is further glycosylated and then cleaved, followed by its transport to th
Immunogenn/a
Other Names[Insulin receptor; IR; CD220; Insulin receptor subunit alpha; Insulin receptor subunit beta; INSR]
Gene, Accession #[INSR], Gene ID: 3643, NCBI: NP_000199.2, UniProt: P06213
Catalog #MBS9212329
Price$165, $370
Order / More InfoINSR (Insulin Receptor) (N-term), 21-52 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGeorge, S., et al., Endocrinology 144(2):631-637 (2003). Longo, N., et al., Hum. Mol. Genet. 11(12):1465-1475 (2002). Hamer, I., et al., Diabetologia 45(5):657-667 (2002). Osawa, H., et al., Clin. Genet. 59(3):194-197 (2001). Rique, S., et al., Clin. Genet. 57(1):67-69 (2000).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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