IFNL3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIFNL3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionCytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection,
ImmunogenImmunogen: Recombinant human Interferon lambda-3 protein (22-196aa)
Other Names[IFN-lambda-3; Cytokine Zcyto22; Interleukin-28B; IL-28B; IL-28C; IFNL3; IL28B; IL28C; ZCYTO22], [IFNL3; IFNL3; IL28B; IL28C; IL-28B; IL28B; IL28C; ZCYTO22; IFN-lambda-3; IL-28B; IL-28C]
Gene, Accession #[IFNL3], Gene ID: 282617, NCBI: NP_742151.2, UniProt: Q8IZI9
Catalog #MBS968924
Price$120, $160
Order / More InfoIFNL3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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