Phospho-JAK1 (Tyr1125) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-JAK1 (Tyr1125) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, ratpredicted: bovine, horse, sheep, rabbit, dog |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-JAK1 (Tyr1125) Antibody detects endogenous levels of JAK1 only when phosphorylated at Tyr1125. Description: Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558). Kinase partner for the interleukin (IL)-2 receptor (PubMed:11909529).Post Translational Modifications: Autophosphorylated (PubMed:7615558). Phosphorylated on tyrosine residues in response to interferon gamma signaling (PubMed:7615558). Dephosphorylation of Tyr-1034 and Tyr-1035 by PTPN2 negatively regulates cytokine-mediated signaling (PubMed:11909529). Ubiquitinated by RNF125; leading to its degradation by the proteasome.Subunit Structure: Interacts with IL31RA (PubMed:15194700). Interac |
| Immunogen | Immunogen: A synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1125. Tissue Specificity: Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue. |
| Other Names | [JAK 1; JAK 1A; JAK 1B; JAK-1; JAK1; JAK1_HUMAN; JAK1A; JAK1B; Janus kinase 1 (a protein tyrosine kinase); Janus kinase 1; JTK3; Tyrosine protein kinase JAK 1; Tyrosine protein kinase JAK1; Tyrosine-protein kinase JAK1] |
| Gene, Accession # | [JAK1], Gene ID: 3716, NCBI: NP_002218.2, UniProt: P23458 |
| Catalog # | MBS9610627 |
| Price | $225, $280, $340 |
| Order / More Info | Phospho-JAK1 (Tyr1125) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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