CRK (CrkII) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CRK (CrkII) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects endogenous levels of CRK and does not cross-react with related proteins. UniPort Summary Function: The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling. Entrez Summary: This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways |
| Immunogen | Immunogen: Purified recombinant human CRK protein fragments expressed in E Coli. Cellular Localization: Cytoplasm; Cell Membrane |
| Other Names | [Proto-oncogene c-Crk; p38; CRKII; adapter molecule crk], [p38; CRKII] |
| Gene, Accession # | [CRK], Gene ID: 1398, NCBI: NP_005197.3, UniProt: P46108 |
| Catalog # | MBS857912 |
| Price | $300 |
| Order / More Info | CRK (CrkII) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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