Hexokinase II Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHexokinase II
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionRabbit IgG polyclonal antibody for Hexokinase-2 (HK2) detection. Background: Hexokinase 2, also known as HK2, is an enzyme which in humans is encoded by the HK2 gene on chromosome 2. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence in the middle region of human Hexokinase II (460-497aa AYRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEME R), different from the related mouse and rat sequences by four amino acids.
Other Names[Hexokinase2; Hexokinase-2; Hexokinase 2; Hexokinase 2 muscle; Hexokinase type II; HK 2; HK2; HK II; HKII; HxK 2; HxK2; P52789], [HK2; HK2; HKII; HXK2; HK II]
Gene, Accession #[HK2], Gene ID: 3099, NCBI: NP_000180.2, UniProt: P52789
Catalog #MBS178645
Price$280
Order / More InfoHexokinase II Antibody from MYBIOSOURCE INC.
Product Specific References1. Entrez Gene: HK2 hexokinase 2.2. Printz RL, Osawa H, Ardehali H, Koch S, Granner DK (Feb 1997). Hexokinase II gene: structure, regulation and promoter organization. Biochemical Society Transactions. 25 (1): 107-12.3. Peng Q, Zhou J, Zhou Q, Pan F, Zhong D, Liang H (2009). Silencing hexokinase II gene sensitizes human colon cancer cells to 5-fluorouracil. Hepato-Gastroenterology. 56 (90): 355-60.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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