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Antigenic Specificity | MUC18 /CD146 / MCAM (Melanoma Cell Adhesion Molecule) |
Clone | [C146/634] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The human CD146 gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. CD146 expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. CD146 is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. |
Immunogen | Immunogen: Recombinant human CD146 protein |
Other Names | [Cell Surface Glycoprotein MUC18, Cell Surface Glycoprotein P1H12, Gicerin, Melanoma Adhesion Molecule (MCAM), Melanoma Associated Glycoprotein MUC18, Melanoma Cell Adhesion Molecule, Melanoma-associated Antigen A32, Mel-CAM, S-endo 1 Endothelial-associated Antigen, Sendo1], [MCAM; MCAM; CD146; MUC18; MUC18] |
Gene, Accession # | [MCAM], Gene ID: 4162, NCBI: NP_006491.2, UniProt: P43121 |
Catalog # | MBS439099 |
Price | $190, $340, $340 |
Order / More Info | MUC18 /CD146 / MCAM (Melanoma Cell Adhesion Molecule) Antibody from MYBIOSOURCE INC. |
Product Specific References | Pruszak J et al. Stem Cells 25:2257-68 (2007 |