Edit |   |
---|---|
Antigenic Specificity | Phospho-GSK3 alpha (Ser21) |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-GSK3 alpha (Ser21) Antibody detects endogenous levels of GSK3 alpha only when phosphorylated at Serine 21. GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase. |
Immunogen | Immunogen: A synthesized peptide derived from human GSK3 alpha around the phosphorylation site of Serine 21 |
Other Names | [DKFZp686D0638; glycogen synthase kinase 3 alpha; Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A] |
Gene, Accession # | [GSK3 alpha], Gene ID: 2931, NCBI: NP_063937.2, UniProt: P49840 |
Catalog # | MBS8511517 |
Price | $290 |
Order / More Info | Phospho-GSK3 alpha (Ser21) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |