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Antigenic Specificity | Human TSH Receptor / TSHR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Gibbon, gorilla, human, monkey |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human TSH Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins. Thyrotropin Receptor, a Glycoprotein Hormone Receptor, plays a central role in controlling thyroid cell metabolism. The TSH receptor can interact with both TSH and autoantibodies against the TSH receptor (thyroid-stimulating immunoglobulins, TSI). Mutations in the receptor are the cause for hyperthyroidism such as gestational hyperthyroidism (hypersensitivity to chorionic gonadotropin) and Grave's disease (autoimmune hyperthyroidism). |
Immunogen | Immunogen Description: Synthetic 16 amino acid peptide from N-terminal extracellular domain of human TSH Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (88%); Cat, Panda (81%). |
Other Names | [TSH Receptor / TSHR (N-Terminus) IHC-plus; TSHR; CHNG1; HTSHR-I; LGR3; Thyrotrophin receptor; TSH-R; TSH receptor; Thyrotropin receptor; Human TSH Receptor; TSHR], [TSHR; TSHR; LGR3; CHNG1; hTSHR-I; LGR3; TSH-R] |
Gene, Accession # | [TSHR], Gene ID: 7253, NCBI: NP_000360.2, UniProt: P16473 |
Catalog # | MBS243961 |
Price | $530 |
Order / More Info | Human TSH Receptor / TSHR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |