TRAF7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTRAF7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: TRAF7 antibody detects endogenous levels of total TRAF7. Function: E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3. Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators. Induces apoptosis when overexpressed.Subunit Structure: Homodimer. Interacts with MAP3K3 and promotes the kinase activity of this enzyme.Post-translational Modifications: Phosphorylated by MAP3K3. Ubiquitinates itself upon phosphorylation.Similarity: Belongs to the WD repeat TRAF7 family.
ImmunogenImmunogen: A synthetic peptide of human TRAF7 Subcellular Location: Cytoplasmic Vesicle. Colocalizes with MAP3K3 to vesicle-like structures throughout the cytoplasm. Tissue Specificity: Ubiquitously expressed with high levels in skeletal muscle, heart, colon, spleen, kidney, liver and placenta.
Other Names[E3 ubiquitin protein ligase TRAF7; E3 ubiquitin-protein ligase TRAF7; RFWD1; Ring finger and WD repeat domain 1; RING finger and WD repeat-containing protein 1; RING finger protein 119; RNF119; TNF receptor associated factor 7; TNF receptor-associated factor 7; TRAF7; TRAF7_HUMAN]
Gene, Accession #[TRAF7], Gene ID: 84231, NCBI: NP_115647.2, UniProt: Q6Q0C0
Catalog #MBS9607831
Price$240, $280
Order / More InfoTRAF7 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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