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Antigenic Specificity | Human CD32 |
Clone | [IV-3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcgammaRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform). |
Immunogen | n/a |
Other Names | [Human CD32; Low affinity immunoglobulin gamma Fc region receptor II-b; FCGR2B; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD32; FCG2; IGFR2] |
Gene, Accession # | [CD32], Gene ID: 2213, NCBI: NP_001002273.1, UniProt: P31994 |
Catalog # | MBS2553865 |
Price | $70, $115 |
Order / More Info | Human CD32 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Stuart S, et al. 1989. EMBO J. 8:3657. 2. Huang Y, et al. 1999. Scand. J. Immunol. 49:177. 3. Hisaka H, et al. 1999. Pathobiology 67:92. |