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Antigenic Specificity | Erk1/2 (Phospho-Thr202/Tyr204) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide binding protein (G protein)-coupled receptors and transforming agents, activate the ERK1 and ERK2 pathways. When growth factors bind to the receptor tyrosine kinase, Ras interacts with Raf, the serine/threonine protein kinase and activates it as well. Once actived, Raf phosphorylates serine residue in 2 further kinases, MEK1/2, which in turn phosphorylates tyrosine/threonine in extracellular-signal regulated kinase (ERK) 1/2. Upon activation, the ERKs either phosphorylate a numbe |
Immunogen | Immunogen: Erk1/2 antibody was raised in Rabbit using Synthetic phospho-peptide as the immunogen |
Other Names | [Rabbit Erk1/2 (Phospho-Thr202/Tyr204); Erk1/2; Erk1/2; MAPK3; mitogen-activated protein kinase 3; BOS_22892; Erk-1; ERK1; Ert2; Esrk1; extracellular signal-regulated kinase 1; extracellular signal-regulated kinase-1; extracellular signal-related kinase 1; fi06b09; HS44KDAP; HUMKER1A; insulin-stimulated MAP2 kinase; MAPK1; MAPK 1; MAPK 3; MAP kinase 1; MAP kinase 3; MAP kinase-activated protein kinase 3; MAP kinase isoform p44; microtubule-associated protein 2 kinase; mitogen-activated 3 (MAP kinase 3; mitogen-activated protein kinase 1; mitogen activated protein kinase 3; mitogen-activated protein kinase 3-like; MNK1; Mtap2k; p44; p44); p44erk1; p44-ERK1; p44mapk; p44-MAPK; p44 MAP kinase; pp42/MAP kinase; PRKM3; zERK1] |
Gene, Accession # | [Erk1/2], NCBI: AEE81046.1 |
Catalog # | MBS5310054 |
Price | $375 |
Order / More Info | Erk1/2 (Phospho-Thr202/Tyr204) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |