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Antigenic Specificity | Phospho-IL-8R beta/CDw128 beta (Ser347) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-IL-8R beta/CDw128 beta (Ser347) antibody detects endogenous levels of IL-8R beta/CDw128 beta only when phosphorylated at Serine 347. Function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.Post-translational Modifications: Phosphorylated upon ligand binding; which is required for desensitization.Similarity: Belongs to the G-protein coupled receptor 1 family. |
Immunogen | Immunogen: A synthesized peptide derived from human IL-8R beta/CDw128 beta around the phosphorylation site of Serine 347 Subcellular Location: Cell Membrane Predicted Cross Reactivity: Pig, Bovine, Dog Similarity: Pig (89%), Bovine (89%), Dog (100%) |
Other Names | [C-X-C chemokine receptor type 2; CD 182; CD182; CD182 antigen; CDw128b; Chemokine (CXC) receptor 2; CMKAR2; CXC-R2; CXCR 2; CXCR-2; CXCR2; CXCR2_HUMAN; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL 8 receptor type 2; IL 8R B; IL-8 receptor type 2; IL-8R B; IL8 RB; IL8 receptor type 2; IL8R B; IL8R2; IL8RA; Interleukin 8 Receptor B; Interleukin 8 receptor, beta; Interleukin 8 receptor, type 2] |
Gene, Accession # | [CXCR2], Gene ID: 3579, NCBI: NP_001161770.1, UniProt: P25025 |
Catalog # | MBS9601009 |
Price | $240, $280 |
Order / More Info | Phospho-IL-8R beta/CDw128 beta (Ser347) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |