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Antigenic Specificity | Phospho-PPP1R12A-S507 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phos |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding S507 of human PPP1R12A Immunogen Species: Human |
Other Names | [M130; MBS; MYPT1] |
Gene, Accession # | [PPP1R12A-S507], Gene ID: 4659, NCBI: NP_001137357.1, UniProt: O14974 |
Catalog # | MBS9135622 |
Price | $235, $350, $525 |
Order / More Info | Phospho-PPP1R12A-S507 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |