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Antigenic Specificity | EpCAM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Epithelial cell adhesion and activating molecule (EpCAM/CD326) is a transmembrane glycoprotein that mediates Ca2+independent, homophilic adhesions on the basolateral surface of most epithelial cells. EpCAM is not expressed in adult squamous epithelium, but it is highly expressed in adeno and squamous cell carcinomas (1). One of the first tumor-associated antigens discovered, EpCAM has long been a marker of epithelial and tumor tissue. Because of its high expression in cancer, EpCAM has become a therapeutic target for human solid tumors of epithelial lineage (reviewed in 2,3). |
Immunogen | Immunogen: A synthetic peptide of human EpCAM |
Other Names | [TACSTD1; EpCAM; EPCAM; DIAR5; EGP2; EGP314; EGP40; ESA; GA7332; HNPCC8; KS1/ 4; KSA; M 4S1; MIC18; MK1; TACSTD1; TROP1; KSA;], [EPCAM; EPCAM; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1; Ep-CAM; EGP; EGP314; hEGP314] |
Gene, Accession # | Gene ID: 4072, NCBI: NP_002345.2, UniProt: P16422 |
Catalog # | MBS125387 |
Price | $235, $350, $525 |
Order / More Info | EpCAM Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Went, P.T. et al. (2004) Hum Pathol 35, 122-8. 2. Baeuerle, P.A. and Gires, O. (2007) Br J Cancer 96, 417-23. 3. Armstrong, A. and Eck, S.L. Cancer Biol Ther 2, 320-6. |