Ras, pan, N,H,K Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Ras, pan, N,H,K |
| Clone | [7H56] |
| Host Species | Rabbit |
| Reactive Species | Drosophila, human, monkey, mouse, rat, yeast |
| Isotype | IgG |
| Format | supernatant |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EL/EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes endogenous levels of human total K-Ras, H-Ras and N-Ras proteins at ~21kD. Species Crossreactivity mouse, monkey, rat, Drosophila, S. cerevisiae. The 21kD guanine-nucleotide binding proteins (K-Ras, H-Ras and N-Ras) cycle between active (GTP-bound) and inactive (GDP-bound) forms. Receptor tyrosine kinases and G-protein-coupled receptors activate Ras, which then stimulates the Raf-MEK-MAPK pathway. GTPase-activating proteins (GAP) normally facilitate the inactivation of Ras. However, in 30% of human tumors, point mutations in Ras prevent the GAP-mediated inhibition of this pathway. The most common oncogenic Ras mutation found in tumors is Gly12 to Asp (G12D), which prevents Ras inactivation, possibly by increasing the overall rigi |
| Immunogen | Immunogen: Synthetic peptide corresponding to residues near the amino terminus of human K-Ras (KLH). |
| Other Names | [-Ras, pan, N,H,K], [Ras85D; C-ras1; CG9375; D-Ras; D-ras-1; D-ras1; D-Ras1; Dm Ras1; DmelCG9375; Dmras85D; dRas; Dras; DRas; dras1; dRas1; dRAS1; Dras1; DRAS1; dRas85D; Dras85D; DRas85D/Ras; E(faf); E(sev)3C; EK3-4; fs(3)05703; l(3)06677; l(3)s1747; p21[Ras1]; ras; Ras; RAS; ras 1;] |
| Gene, Accession # | Gene ID: 41140, NCBI: NP_476699.1 |
| Catalog # | MBS605436 |
| Price | $550 |
| Order / More Info | Ras, pan, N,H,K Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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