Rabbit BTK (Phospho-Tyr223) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Rabbit BTK (Phospho-Tyr223) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-BTK(Tyr223) Antibody detects endogenous levels of BTK only when phosphorylated at Tyrosine 223. Background: Defects in the Bruton tyrosine kinase (BTK) gene cause Agammaglobulinemia. Agammaglobulinemia is an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. Function: Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling path |
| Immunogen | Immunogen: A synthesized peptide derived from human BTK around the phosphorylation site of Tyrosine 223. |
| Other Names | [Agammaglobulinaemia tyrosine kinase; AGMX1; ATK; B cell progenitor kinase; BPK; Bruton's tyrosine kinase; EC 2.7.10.2; kinase Btk; Kinase EMB], [BTK; BTK; AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1; AGMX1; ATK; BPK; ATK; BPK] |
| Gene, Accession # | [BTK], Gene ID: 695, NCBI: NP_000052.1, UniProt: Q06187 |
| Catalog # | MBS000637 |
| Price | $440, $715 |
| Order / More Info | Rabbit BTK (Phospho-Tyr223) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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