Mouse Tbk1 (N-term), 8-35 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse Tbk1 (N-term), 8-35 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Tbk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-35 amino acids from the N-terminal region of mouse Tbk1. Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central fac |
| Immunogen | n/a |
| Other Names | [Serine/threonine-protein kinase TBK1; T2K; TANK-binding kinase 1; Tbk1] |
| Gene, Accession # | [Tbk1], Gene ID: 56480, NCBI: NP_062760.3, UniProt: Q9WUN2 |
| Catalog # | MBS9203960 |
| Price | $165, $370 |
| Order / More Info | Mouse Tbk1 (N-term), 8-35 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Parvatiyar, K., et al. J. Biol. Chem. 285(20):14999-15009(2010) Watanabe, T., et al. J. Clin. Invest. 120(5):1645-1662(2010) Gabhann, J.N., et al. J. Immunol. 184(5):2314-2320(2010) Munoz, M.C., et al. J. Endocrinol. 201(2):185-197(2009) Miyahira, A.K., et al. J. Immunol. 182(4):2248-2257(2009) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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