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Antigenic Specificity | POU3F2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse |
Isotype | n/a |
Format | Protein A purified |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | POU3F2 is a developmental neural cell-specific POU domain transcription factor and is crucial for cell lineage determination. In melanoma lesions, cells expressing high levels of POU3F2 show enhanced invasive and metastatic capacity that can in part be explained by repression of MITF (Micropthalmia-associated Transcription Factor) expression via POU3F2 binding to its promoter. POU3F2 is expressed exclusively in the central nervous system, more specifically in postmitotic neurons and glia. |
Immunogen | Immunogen Information: A partial length recombinant POU3F2 protein (amino acids 220-421) was used as the immunogen for this antibody. |
Other Names | [POU3F2; BRN2; OCT7; OTF7; Brain-specific homeobox/POU domain protein 2; Nervous system-specific octamer-binding transcription factor N-Oct-3; Oct-7; Octamer-binding protein 7; OTF-7; Octamer-binding transcription factor 7; to POU3F2; POU3F2; POU3F2], [POU3F2; POU3F2; BRN2; OCT7; OTF7; OTF-7; POUF3; brn-2; oct-7; N-Oct3; BRN2; OCT7; OTF7; Brain-2; Brn-2; Oct-7; OTF-7] |
Gene, Accession # | [POU3F2], Gene ID: 5454, NCBI: P20265.4, UniProt: P20265 |
Catalog # | MBS668756 |
Price | $140, $270 |
Order / More Info | POU3F2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |