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Antigenic Specificity | VASP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: VASP (phospho-Ser238) antibody detects endogenous levels of VASP only when phosphorylated at serine 238. Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling |
Immunogen | Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human VASP around the phosphorylation site of serine 238 (K-V-SP-K-Q). |
Other Names | [vasodilator-stimulated phosphoprotein; Vasodilator-stimulated phosphoprotein; vasodilator-stimulated phosphoprotein; vasodilator-stimulated phosphoprotein], [VASP; VASP] |
Gene, Accession # | [VASP], Gene ID: 7408, NCBI: NP_003361.1 |
Catalog # | MBS416889 |
Price | $325 |
Order / More Info | VASP Antibody from MYBIOSOURCE INC. |
Product Specific References | Zhao WM, et al. (2001) EMBO J; 20(9): 2315-2325Millard TH, et al. (2005) EMBO J; 24(2): 240-250Khnel K, et al. (2004) Proc Natl Acad Sci U S A; 101(49): 17027-17032Haffner C, et al. (1995) EMBO J; 14(1): 19-27Ramesh N, et al. (1997) Proc Natl Acad Sci U S A; 94(26): 14671-14676 |