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Antigenic Specificity | BIRC7 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, human, rabbit |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against BIRC7. It was validated on Western Blot using a cell lysate as a positive control.Target Description: BIRC7 protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BIRC7 |
Other Names | [baculoviral IAP repeat-containing protein 7 isoform alpha; Baculoviral IAP repeat-containing protein 7; baculoviral IAP repeat-containing protein 7; baculoviral IAP repeat containing 7; Kidney inhibitor of apoptosis protein; KIAP; Livin; Melanoma inhibitor of apoptosis protein; ML-IAP; RING finger protein 50] |
Gene, Accession # | [BIRC7], Gene ID: 79444, NCBI: NP_647478, UniProt: Q96CA5 |
Catalog # | MBS3224348 |
Price | $335 |
Order / More Info | BIRC7 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |