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Antigenic Specificity | DNAJB6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity. |
Immunogen | Immunogen: Recombinant Human DnaJ homolog subfamily B member 6 protein (208-326AA) |
Other Names | [DnaJ homolog subfamily B member 6; HHDJ1; Heat shock protein J2; HSJ-2; MRJ; MSJ-1; DNAJB6; HSJ2; MRJ; MSJ1] |
Gene, Accession # | [DNAJB6], Gene ID: 10049, NCBI: NP_005485.1, UniProt: O75190 |
Catalog # | MBS7049417 |
Price | $160, $235 |
Order / More Info | DNAJB6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |