Phospho-MET-Y1234 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-MET-Y1234
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionMet, a high affinity tyrosine kinase receptor for hepatocyte growth factor (HGF, also known as scatter factor) is a disulfide-linked heterodimer made of 45 kDa alpha- and 145 kDa beta-subunits (1,2). The alpha-subunit and the amino-terminal region of the beta-subunit form the extracellular domain. The remainder of the beta-chain spans the plasma membrane and contains a cytoplasmic region with tyrosine kinase activity. Interaction of Met with HGF results in autophosphorylation at multiple tyrosines, which recruit several downstream signaling components, including Gab1, c-Cbl, and PI3 kinase (3). These fundamental events are important for all of the biological functions involving Met kinase activity. The addition of a phosphate at cytoplasmic
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding Y1234 of human MET
Other Names[Phospho-MET-Y1234: HGFR; AUTS9; RCCP2; c-Met], [MET; MET; HGFR; AUTS9; RCCP2; c-Met; HGF receptor; SF receptor]
Gene, Accession #[MET], Gene ID: 4233, NCBI: P08581.4, UniProt: P08581
Catalog #MBS125905
Price$235, $350, $525
Order / More InfoPhospho-MET-Y1234 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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