CLEC4E Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCLEC4E
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatfluorescein (FITC) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionC-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
ImmunogenImmunogen: Recombinant human C-type lectin domain family 4 member E protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161488
Other Names[C-type lectin domain family 4 member E; CLEC4E; CLECSF9; MINCLE; UNQ218/PRO244; C-type lectin superfamily member 9; Macrophage-inducible C-type lectin], [CLEC4E; CLEC4E; MINCLE; CLECSF9; CLECSF9; MINCLE]
Gene, Accession #[CLEC4E], Gene ID: 26253, NCBI: NP_055173.1, UniProt: Q9ULY5
Catalog #MBS1493146
Price$160, $235
Order / More InfoCLEC4E Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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