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Antigenic Specificity | CLEC4E |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B. |
Immunogen | Immunogen: Recombinant human C-type lectin domain family 4 member E protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161488 |
Other Names | [C-type lectin domain family 4 member E; CLEC4E; CLECSF9; MINCLE; UNQ218/PRO244; C-type lectin superfamily member 9; Macrophage-inducible C-type lectin], [CLEC4E; CLEC4E; MINCLE; CLECSF9; CLECSF9; MINCLE] |
Gene, Accession # | [CLEC4E], Gene ID: 26253, NCBI: NP_055173.1, UniProt: Q9ULY5 |
Catalog # | MBS1493146 |
Price | $160, $235 |
Order / More Info | CLEC4E Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |