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Antigenic Specificity | MER/SKY (Phospho-Tyr749/681) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of MER/SKY only when phosphorylated at tyrosine 749/681. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). Graham D.K., Cell Growth Differ. 5:647-657(1994).Gal A., Nat. Genet. 26:270-271(2000).Hillier L.W., Nature 434:724-731(2005). |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 749/681(K-I-Y(p)-S-G) derived from Human MER/SKY. |
Other Names | [C-mer; MERK; MERTK] |
Gene, Accession # | [MER/SKY], Gene ID: 10461, NCBI: NP_006334.2, UniProt: Q12866 |
Catalog # | MBS9406153 |
Price | $200, $255 |
Order / More Info | MER/SKY (Phospho-Tyr749/681) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |