Non-Phospho-VEGFR-2 (Paired Y951) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Non-Phospho-VEGFR-2 (Paired Y951) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes ~200 kDa of human VEGFR-2 protein without a phosphorylation site of Tyrosine 951. It does not recognize phosphorylated peptides. This antibody also reacts with mouse. The other species are not tested. Vascular endothelial growth factor receptor-2 (VEGFR-2), also known as CD309 antigen, the earliest known marker for vascular endothelia cells, is essential in vasculogenesis and angiogenesis. Binding of the dimeric VEGF-A to the extracellular domains of two monomeric receptors induces dimerization and activation of tyrosine kinase at tyrosine residues Y951, Y1054 and Y1059 in the kinase domain serve as positive regulatory sites. Phosphorylation at Y951 of the kinase insert is related to the migration of endothelial cel |
| Immunogen | Antigen Preparation: A synthetic peptide corresponding to the epitope -KDYVG- without a Tyr951 phosphorylation site of human VEGFR-2 protein. This sequence is identical within human, mouse and dog. |
| Other Names | [Rabbit VEGFR-2; Vascular endothelial growth factor receptor 2 (VEGFR-2); KDR/ Flk-1; CD309 antigen], [KDR; KDR; FLK1; CD309; VEGFR; VEGFR2; FLK1] |
| Gene, Accession # | [VEGFR-2 (Paired Y951) (CD309)], Gene ID: 3791, NCBI: NP_002244.1, UniProt: P35968 |
| Catalog # | MBS462219 |
| Price | $265 |
| Order / More Info | Non-Phospho-VEGFR-2 (Paired Y951) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Taro Matsumoto, et al. VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis. The EMBO Journal (2005) 24, 2342-2353 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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