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Antigenic Specificity | CD137/4-1BB/TNFRSF9 |
Clone | [4-1BB/3201] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment, and has been implicated in breast cancer, melanoma and lymphoma. |
Immunogen | Immunogen: A recombinant fragment (around aa 19-188) of human CD137/4-1BB/TNFRSF9 protein (exact sequence is proprietary) |
Other Names | [4-1BB Ligand Receptor T Cell; Antigen 4-1BB Homolog; CDw137; HLDA VI; Homolog of Mouse 4 1BB; induced by lymphocyte activation (ILA); Interleukin activated receptor homolog of Mouse Ly63; T-cell antigen 4-1BB/ILA homolog; Tumor necrosis factor receptor superfamily member 9] |
Gene, Accession # | [TNFRSF9], Gene ID: 3604, NCBI: NP_001552.2, UniProt: Q07011 |
Catalog # | MBS4381020 |
Price | $190, $340, $340 |
Order / More Info | CD137/4-1BB/TNFRSF9 Antibody from MYBIOSOURCE INC. |
Product Specific References | Zhao S, et al. CD137 ligand is expressed in primary and secondary lymphoid follicles and in B-cell lymphomas: diagnostic and therapeutic implications. Am J Surg Pathol. 2013 Feb;37(2):250-8. |