CD137/4-1BB/TNFRSF9 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD137/4-1BB/TNFRSF9
Clone[4-1BB/3201]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsELISA (EIA), Immunofluorescence (IF), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment, and has been implicated in breast cancer, melanoma and lymphoma.
ImmunogenImmunogen: A recombinant fragment (around aa 19-188) of human CD137/4-1BB/TNFRSF9 protein (exact sequence is proprietary)
Other Names[4-1BB Ligand Receptor T Cell; Antigen 4-1BB Homolog; CDw137; HLDA VI; Homolog of Mouse 4 1BB; induced by lymphocyte activation (ILA); Interleukin activated receptor homolog of Mouse Ly63; T-cell antigen 4-1BB/ILA homolog; Tumor necrosis factor receptor superfamily member 9]
Gene, Accession #[TNFRSF9], Gene ID: 3604, NCBI: NP_001552.2, UniProt: Q07011
Catalog #MBS4381020
Price$190, $340, $340
Order / More InfoCD137/4-1BB/TNFRSF9 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesZhao S, et al. CD137 ligand is expressed in primary and secondary lymphoid follicles and in B-cell lymphomas: diagnostic and therapeutic implications. Am J Surg Pathol. 2013 Feb;37(2):250-8.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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