FLASH Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-FLASH antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | FLASH |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | FLASH Antibody: A novel mammalian CED-4 homologous was recently identified and cloned in mouse and human and designated FLASH (for FLICE-associated huge protein). FLASH is involved in Fas induced apoptosis. It is recruited to Fas after the receptor cross-linking. Overexpression of wild type of FLASH facilitates and its dominant negative form inhibits Fas induced apoptosis. FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8. There are parallels between FLASH and Apaf-1/CED-4 although there are arguments against their structural similarity. FLASH is widely expressed. |
| Immunogen | Immunogen: FLASH antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human FLASH which differ from those of mouse by one amino acid. Buffer: FLASH Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [FLASH; CED-4; FLASH; RIP25; KIAA1315; CASP8-associated protein 2; FLICE-associated huge protein; caspase 8 associated protein 2], [CASP8AP2; CASP8AP2; CED-4; FLASH; RIP25] |
| Gene, Accession # | [CASP8AP2], Gene ID: 9994, NCBI: AF165161, UniProt: Q9UKL3 |
| Catalog # | MBS150625 |
| Price | $375 |
| Order / More Info | FLASH Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies