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Antigenic Specificity | IL6ST |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total IL6ST protein. The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have |
Immunogen | Immunogen: Fusion protein of human IL6ST Immunogen Type: Protein |
Other Names | [CD130; GP130; CDW130; IL-6RB] |
Gene, Accession # | [IL6ST], Gene ID: 3572, NCBI: NP_001177910.1, UniProt: P40189 |
Catalog # | MBS9417042 |
Price | $255 |
Order / More Info | IL6ST Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |