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Antigenic Specificity | RIP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-RIP3 [Rabbit antibody to peptide corresponding to aa 473-486 of mouse RIP3.]. This antibody recognizes mouse and rat RIP3 (57 kD). Serine/threonine protein kinases, such as ASK1, RIP, DAP and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins, including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two members of the family of death receptors. A novel member in the RIP kinase family has been identified and designated RIP3. RIP3 contains a Nterminal kinase domain, but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, mediates TNFR1-induced apoptosis, and attenuates RIP and TNFR1-induced NF- kappa B activation. The messenger RNA of RIP3 is found i |
Immunogen | Antigen: Peptide corresponding to aa 473- 486 of mouse RIP3. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS194135 |
Price | $415 |
Order / More Info | RIP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |