CELA3B/ELA3B (Pancreatic Function Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CELA3B/ELA3B (Pancreatic Function Marker) |
| Clone | [CELA3B/1257] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat. |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAb recognizes a protein of ~30kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of c |
| Immunogen | Immunogen: Recombinant human CELA3B protein fragment (aa82-238). Cellular Localization: Cytoplasmic |
| Other Names | [Chymotrypsin like elastase family member 3B (CELA3B); ELA3B; Elastase IIIB; Protease E], [ELA3B] |
| Gene, Accession # | [CELA3B], Gene ID: 23436, NCBI: NP_031378.1, UniProt: P08861 |
| Catalog # | MBS439968 |
| Price | $190, $340, $340 |
| Order / More Info | CELA3B/ELA3B (Pancreatic Function Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Shirasu, Y., et al. 1988. Molecular cloning of complementary DNA encoding one of the human pancreatic protease E isozymes. J. Biochem. 104:259-264. Tani, T., et al. 1988. Identification of a novel class of elastase isozyme, human pancreatic elastase III, by cDNA and genomic gene cloning. J. Biol. Chem. 263: 1231-1239. Shimada, S., et al. 2002. Pancreatic elastase IIIA and its variants are expressed in pancreatic carcinoma cells. Int. J. Mol. Med. 10: 599-603. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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