Edit |   |
---|---|
Antigenic Specificity | MMP12 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MMP12 |
Other Names | [macrophage metalloelastase preproprotein; Macrophage metalloelastase; macrophage metalloelastase; matrix metallopeptidase 12; Macrophage elastase; ME; hME; Matrix metalloproteinase-12] |
Gene, Accession # | [MMP12], Gene ID: 4321, NCBI: NP_002417.2, UniProt: P39900 |
Catalog # | MBS3221029 |
Price | $335 |
Order / More Info | MMP12 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |