Dc-Sign/CD 209 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Dc-Sign/CD 209 |
| Clone | [ABM47B7] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b kappa |
| Format | Protein G purified |
| Size | 0.025 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) is a tetrameric C-type (calcium-dependent) lectin that binds, through its C-terminal carbohydrate recognition domain, high mannose N-linked glycans present on the surface of several viral glycoproteins such as human immunodeficiency virus (HIV) gp120 and hepatitis C virus (HCV) E2. It facilitates DC-specific delivery of Ag. This is accomplished by conjugating Ag to receptor-specific Ab or carbohydrate ligands that bind to its carbohydrate recognition domain. In humans, DC-SIGN expression is restricted to DCs and certain types of macrophages. DC-SIGN is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, incl |
| Immunogen | Immunogen Information: A recombinant protein fragment of DC-Sign protein was used as the immunogen for this antibody. |
| Other Names | [CD209; CLEC4L; C-type lectin domain family 4 member L; DC-SIGN; Dendritic cell-specific ICAM-3-grabbing non-integrin 1; to Dc-Sign; Dc-Sign; Dc-Sign], [CD209; CD209; CDSIGN; CLEC4L; DC-SIGN; DC-SIGN1; CLEC4L; DC-SIGN; DC-SIGN1] |
| Gene, Accession # | [CD209], Gene ID: 30835, NCBI: Q9NNX6.1, UniProt: Q9NNX6 |
| Catalog # | MBS668318 |
| Price | $145, $290 |
| Order / More Info | Dc-Sign/CD 209 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Wai K. Lai, Phoebe J. Sun, Jie Zhang, Adam Jennings, Patricia F. Lalor, Stefan Hubscher, Jane A. McKeating, and David H. Adams. Expression of DC-SIGN and DC-SIGNR on Human Sinusoidal Endothelium Am J Pathol. 2006 Jul; 169(1): 200-208.doi: 10.2353/ajpath.2006.051191 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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