GABBR1 (N-Term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGABBR1 (N-Term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshumanpredicted: amphibian
Isotypen/a
Formatunconjugated
Size0.05 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis GABBR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 18-52 amino acids from human GABBR1. Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysi
Immunogenn/a
Other Names[Purified Rabbit (Pab); Gamma-aminobutyric acid type B receptor subunit 1; GABA-B receptor 1; GABA-B-R1; GABA-BR1; GABABR1; Gb1; GABBR1; GPRC3A]
Gene, Accession #[GABBR1], Gene ID: 2550, NCBI: NP_001461.1, UniProt: Q9UBS5
Catalog #MBS9216245
Price$165, $370
Order / More InfoGABBR1 (N-Term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKaupmann K.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:14991-14996(1998).White J.H.,et al.Nature 396:679-682(1998).Stropp U.,et al.Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.Grifa A.,et al.Biochem. Biophys. Res. Commun. 250:240-245(1998).Goei V.L.,et al.Biol. Psychiatry 44:659-666(1998).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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