FZD7 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FZD7 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: FZD7 antibody detects endogenous levels of total FZD7. Function: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular trans |
| Immunogen | Immunogen: A synthesized peptide derived from human FZD7 Subcellular Location: Membrane. Tissue Specificity: High expression in adult skeletal muscle and fetal kidney, followed by fetal lung, adult heart, brain, and placenta. Specifically expressed in squamous cell esophageal carcinomas. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (82%), Xenopus (82%) |
| Other Names | [Frizzled 7, seven transmembrane spanning receptor; frizzled class receptor 7; Frizzled drosophila homolog of 7; Frizzled family receptor 7; Frizzled homolog 7; Frizzled-7; Frizzled7; Fz 7; Fz-7; Fz7; FZD 7; FZD7; FZD7_HUMAN; FzE 3; FzE3; hFz 7; hFz7; Homolog of Drosophila Frizzled 7; OTTHUMP00000163742] |
| Gene, Accession # | [FZD7], Gene ID: 8324, NCBI: NP_003498.1, UniProt: O75084 |
| Catalog # | MBS9608974 |
| Price | $240, $280 |
| Order / More Info | FZD7 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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