Phospho-Vinculin (Tyr692) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-Vinculin (Tyr692)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, horse, sheep, rabbit, dog, chicken
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Peptide ELISA (EIA)
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DescriptionSpecificity: Phospho-Vinculin (Tyr692) Antibody detects endogenous levels of Vinculin only when phosphorylated at Tyr692. Description: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.Post Translational Modifications: Phosphorylated; on serines, threonines and tyrosines. Phosphorylation on Tyr-1133 in activated platelets affects head-tail interactions and cell spreading but has no effect on actin binding nor on localization to focal adhesion plaques (By similarity). Acetylated; mainly by myristic acid but also by a small
ImmunogenImmunogen: A synthesized peptide derived from human Vinculin around the phosphorylation site of Tyr692. Tissue Specificity: Metavinculin is muscle-specific.
Other Names[CMD1W; CMH15; Epididymis luminal protein 114; HEL114; Metavinculin; MV; MVCL; OTTHUMP00000019861; OTTHUMP00000019862; VINC; VINC_HUMAN; Vinculin]
Gene, Accession #[VCL], Gene ID: 7414, NCBI: NP_003364.1, UniProt: P18206
Catalog #MBS9610611
Price$225, $280, $340
Order / More InfoPhospho-Vinculin (Tyr692) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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