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Antigenic Specificity | Phospho-Vinculin (Tyr692) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, horse, sheep, rabbit, dog, chicken |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Vinculin (Tyr692) Antibody detects endogenous levels of Vinculin only when phosphorylated at Tyr692. Description: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.Post Translational Modifications: Phosphorylated; on serines, threonines and tyrosines. Phosphorylation on Tyr-1133 in activated platelets affects head-tail interactions and cell spreading but has no effect on actin binding nor on localization to focal adhesion plaques (By similarity). Acetylated; mainly by myristic acid but also by a small |
Immunogen | Immunogen: A synthesized peptide derived from human Vinculin around the phosphorylation site of Tyr692. Tissue Specificity: Metavinculin is muscle-specific. |
Other Names | [CMD1W; CMH15; Epididymis luminal protein 114; HEL114; Metavinculin; MV; MVCL; OTTHUMP00000019861; OTTHUMP00000019862; VINC; VINC_HUMAN; Vinculin] |
Gene, Accession # | [VCL], Gene ID: 7414, NCBI: NP_003364.1, UniProt: P18206 |
Catalog # | MBS9610611 |
Price | $225, $280, $340 |
Order / More Info | Phospho-Vinculin (Tyr692) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |