Phospho-RPS6KA5-S376.ctrl Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-RPS6KA5-S376.ctrl
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human. Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cyto
Immunogenn/a
Other Names[Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKL; RPS6KA5; MSK1]
Gene, Accession #[RPS6KA5], Gene ID: 9252, NCBI: NP_004746.2, UniProt: O75582
Catalog #MBS9204878
Price$165, $370
Order / More InfoPhospho-RPS6KA5-S376.ctrl Antibody from MYBIOSOURCE INC.
Product Specific ReferencesDeak M.,et al.EMBO J. 17:4426-4441(1998). New L.,et al.J. Biol. Chem. 274:1026-1032(1999). Jiang C.,et al.Cytogenet. Cell Genet. 87:261-262(1999). Heilig R.,et al.Nature 421:601-607(2003). Wiggin G.R.,et al.Mol. Cell. Biol. 22:2871-2881(2002).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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